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Examples of drugs which can be used for sedation include isoflurane, propofol, etomidate, ketamine, fentanyl, lorazepam and midazolam.

Sedation is typically used in minor surgical procedures such as endoscopy, vasectomy, or dentistry and for reconstructive surgery, some cosmetic surgeries, removal of wisdom teeth, or for high-anxiety patients.

Typically, levels are (i) agitation, (ii) calm, (iii) responsive to voice alone, (iv) responsive to tactile stimulation, (v) responsive to painful stimulation only, and (vi) unresponsive to painful stimulation.

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Many sedatives can be misused, but barbiturates and benzodiazepines are responsible for most of the problems with sedative use due to their widespread recreational or non-medical use.

People who have difficulty dealing with stress, anxiety or sleeplessness may overuse or become dependent on sedatives.

They are central nervous depressants and interact with brain activity causing its deceleration.

Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA), which are brain chemicals performing communication between brain cells.

They increase tractability and compliance of children or troublesome or demanding patients.

Some sedatives can cause psychological and physical dependence when taken regularly over a period of time, even at therapeutic doses.

Others take sedatives recreationally to relax and forget their worries.

Barbiturate overdose is a factor in nearly one-third of all reported drug-related deaths.

Some heroin users may take them either to supplement their drug or to substitute for it.

Stimulant users may take sedatives to calm excessive jitteriness.

1974) and the RASS (Richmond Agitation-Sedation Scale).

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