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Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

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They increase tractability and compliance of children or troublesome or demanding patients.

Some sedatives can cause psychological and physical dependence when taken regularly over a period of time, even at therapeutic doses.

In addition to the aforementioned precautions, patients should be interviewed to determine if they have any other condition that may lead to complications while undergoing treatment.

Any head, neck, or spinal cord injuries should be noted as well as any diagnosis of osteoporosis.

Others take sedatives recreationally to relax and forget their worries.

Barbiturate overdose is a factor in nearly one-third of all reported drug-related deaths.

Some heroin users may take them either to supplement their drug or to substitute for it.

Stimulant users may take sedatives to calm excessive jitteriness.

Doses of sedatives such as benzodiazepines, when used as a hypnotic to induce sleep, tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.

Sedatives can be misused to produce an overly-calming effect (alcohol being the classic and most common sedating drug).

Many sedatives can be misused, but barbiturates and benzodiazepines are responsible for most of the problems with sedative use due to their widespread recreational or non-medical use.

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